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Dilemma sa dugotrajnom ili prekomernom upotrebom bensedina je u tome što benzodiazepini mogu izazvati osiromašenje GABA receptora. Ovo na kraju može imati obrnut efekat na mozak, čineći da neko iskusi hiper-ekscitabilnost.It may be coupled with an NSAID for instance Ibuprofen and anti-sickness medication which makes it quite powerful at deliv